Antibiotic usage in surgical prophylaxis: a prospective surveillance of surgical wards at a tertiary hospital in Malaysia.

نویسندگان

  • Ai Ling Oh
  • Leh Min Goh
  • Nik Abdullah Nik Azim
  • Chee Sian Tee
  • Chee Wei Shehab Phung
چکیده

INTRODUCTION The widespread and inappropriate use of broad-spectrum antibiotics in surgical prophylaxis has led to reduced treatment efficacy, increased healthcare costs, and antibiotic resistance. This study aimed to explore the adherence of antibiotic usage in surgical prophylaxis to the national antibiotic guideline and the incidences of surgical site infection (SSI). METHODOLOGY A three-month prospective observational study has been conducted in the surgical wards of Sarawak General Hospital (SGH) using a standardized surveillance form. Each patient was reviewed for up to 30 days post-operatively to determine the occurrence of SSI. RESULTS A total of 87 patients were included within the study period. The majority of the cases were clean-contaminated wounds (60.9%). Most were hepatobiliary cases (37.9%), followed by colorectal cases (19.5%). The most preferred antibiotic used was cefoperazone (63.2%). The choices of antibiotics in 78.2% of the cases were consistent with the guideline. Around 80% of prophylactic antibiotics were given within one hour before operation and 27.6% were omitted from intraoperative re-dosing. Prophylactic antibiotics were discontinued within 24 hours post-operatively in 77% of the cases. Of those continued for > 24 hours, the majority (60%) were administered for unknown reasons. SSI was documented in 13.8% of the total cases studied. However, there was no significant association between choices of antibiotics and timing of surgical prophylaxis with SSI (p = 0.299 and p = 0.258 respectively). CONCLUSION Overall guideline adherence rate was more than 70%. Areas of non-concordance to the guideline require further investigation.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

بررسی کارایی دو روش پایش در تشخیص عفونت زخم در بخش‌های جراحی عمومی بیمارستان امام‌خمینی

Background: Surgical wound infection surveillance is an important facet of hospital infection control processes. There are several surveillance methods for surgical site infections. The objective of this study is to evaluate the accuracy of two different surgical site infection surveillance methods. Methods: In this prospective cross sectional study 3020 undergoing surgey in general surgical w...

متن کامل

Appropriate use of vancomycin in an educational tertiary care hospital in Tehran, Iran

 Abstract Background: Inappropriate prescription of vancomycin has been shown to be asso- ciated with induction of antibiotic resistance. The objective of this study was to deter- mine the incidence of inappropriate use of vancomycin in a tertiary care hospital in Iran. Methods: A descriptive cross-sectional investigation was performed from September 2004 to March 2005 in all units of a general...

متن کامل

Prophylactic Antibiotics in Otolaryngologic Surgeries: From Knowledge to Practice

Introduction: The management and use of antimicrobial drugs has clinical, economic, and environmental implications. In many countries, antimicrobial drugs are the most frequently prescribed therapeutic agents. Therefore, health-care policy should focus on how to establish a rational attitude toward antibiotics. This study was performed to investigate antibiotic usage as a prophylactic regimen ...

متن کامل

Risk Factors for Surgical Site Infection After Appendectomy for Acute Appendicitis; Results of a Cross-Sectional Study Carried out at a Community Hospital in Qatar (2013-2016)

Background: Identifying risk factors for surgical site infection (SSI) after appendectomies could be useful in focusing prevention programs. Objective: The current study aimed to identify the risk factors associated with SSI in a cohort of patients from a single center in Western Qatar. Methods: This cross-sectional study was carrie...

متن کامل

بررسی عوامل خطرساز برای عفونت محل جراحی در بیماران جراحی اعصاب تحت پروفیلاکسی آنتی‌بیوتیکی

    Background and Aim: Surgical site infection (SSI) is one of the most common complications in patients undergoing surgery, increasing the mortality and morbidity rates in surgical wards. This prospective study aimed to determine the incidence and the main risk factors of SSI after neurosurgical procedures in patients on antibiotic prophylaxis in a teaching hospital at Tehran, Iran.Patients a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of infection in developing countries

دوره 8 2  شماره 

صفحات  -

تاریخ انتشار 2014